Chronic inorganic arsenic (iAs) exposure affects > 220 million people worldwide and skin cancer is a hallmark of long-term iAs exposure. Limited information exists regarding arsenic methylation by human keratinocytes and how methylation influences skin carcinogenesis. Inorganic arsenite (iAs III ) and its methylated metabolites disrupt diverse zinc finger proteins, leading to differential toxicity patterns. We examined arsenic...

When quantifying changes over time in the natural environment, the stability of the observations used should be considered. Stability conceptually refers to how accurately true geophysical changes and trends are reflected in observational data. We argue the need for a better approach to defining and quantifying stability consistently across climate data records. We propose that the appropriate stability metric is the stability...

Earth observation data should inform decision making, but good decisions can only be made if the uncertainties in the data are taken into account. Making sense of uncertainty information can be difficult, because uncertainties represent the statistical spread in the observations (e.g., expressed as $$x \pm y$$ x ± y ), which does not relate directly to one specific use case of the data. Here, we propose a Bayesian framework to...

Sport-related brain injury is very common, and the potential long-term effects include a wide range of neurological and psychiatric symptoms, and potentially neurodegeneration. Around the globe, researchers are conducting neuroimaging studies on primarily homogenous samples of athletes. However, neuroimaging studies are expensive and time consuming, and thus current findings from studies of sport-related brain injury are often...

To support calibration and validation of satellite sea surface temperature (SST) retrievals, over 60 high-resolution SST (HRSST) drifting buoys were deployed at sea between 2012 and 2017. Their data record is reviewed here. It is confirmed that sea state and immersion depth play an important role in understanding the data collected by such buoys and that the SST sensors need adequate insulation. In addition, calibration verifi...

Heat fluxes at the lake surface play an integral part in determining the energy budget and thermal structure in lakes, including regulating how lakes respond to climate change. We explore patterns in turbulent heat fluxes, which vary across temporal and spatial scales, using in situ high‐frequency monitoring data from 45 globally distributed lakes. Our analysis demonstrates that some of the lakes studied follow a marked season...

Major changes are occurring across the North Atlantic climate system, including in the atmosphere, ocean and cryosphere, and many observed changes are unprecedented in instrumental records. As the changes in the North Atlantic directly affect the climate and air quality of the surrounding continents, it is important to fully understand how and why the changes are taking place, not least to predict how the region will change in...

Lake surface water temperatures ( LSWTs ) of 246 globally distributed large lakes were derived from Along‐Track Scanning Radiometers ( ATSR ) for the period 1991–2011. The climatological cycles of mean LSWT derived from these data quantify on a global scale the responses of large lakes' surface temperatures to the annual cycle of forcing by solar radiation and the ambient meteorological conditions. LSWT cycles reflect the twic...

Numerous anthropogenic factors represent environmental threats to Gulf Coast wetland ecosystems and associated fauna. American alligators (Alligator mississippiensis) have been subject to long-term management and used as ecological and physiological indicators of habitat quality in response to anthropogenic events and stochastic natural disasters. The present study monitored heterophil to lymphocyte ratios (an indicator of str...