Immunogenic cell death (ICD) can activate immune cells and potentiate the response to immunotherapy. The mitogen-activated protein kinase (MAPK) signaling pathway regulates the immune response and mediates T-cell receptor signaling. Activation of the MAPK signaling pathway decreases the levels of tumor-infiltrating lymphocytes in triple-negative breast cancer (TNBC) and is associated with worse survival. Here, we investigated...

Peripheral nerve injury (PNI) significantly impairs patients’ quality of life, with elderly individuals experiencing particularly severe consequences due to aging-related declines in neuronal injury response and repair capabilities. Processes of the generation and transmission of injury signals, axonal disruption, initiation of regeneration, and the elongation of regenerating axons, as well as the subsequent reinnervation by t...

This study explores how Taiwan's climate might change in the future, using statistical downscaling techniques to make global climate projection data more relevant to the region. Global climate models often lack the fine detail necessary for small areas, such as Taiwan, particularly given its unique geography and local weather systems. To address this, we used statistical methods to create high‐resolution projections that combi...