(1) Background: Klotho is a multifunctional protein, but its biophysiological roles during fish early development are unclear. (2) Methods: We carried out anti-sense Klotho morpholino injection and whole-mount in situ hybridization experiments in this study. (3) Results: Our results showed that in the Klotho MO1-injected group, embryos displayed longitudinal shapes and swelling yolks compared to those of the un-injected groups...

In-depth analysis of metabolomics diversity of marine species through advanced mass spectrometric analysis is one of the most promising new tools for the development of marine drugs against mild and life-threatening diseases. Neurofibromas are a common type of tumor in the peripheral nervous system. Currently, there are very limited treatment options for neurofibromas. In our course of exploring potential therapeutic agents fo...

In contrast to either considering structures with full degrees of freedom but with wave force on mooring lines neglected or with wave scattering and radiation neglected, in this paper, a new analytic solution is presented for wave interaction with moored structures of full degrees of freedom and with wave forces acting on mooring lines considered. The linear potential wave theory is applied to solve the wave problem. The wave...