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Author: Chun-Qing Zhang ×Clear All Filters
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Novel prenylated diketopiperazines with anti-osteoclastogenic activity from the deep-sea-derived Penicillium limosum ZEN48NARA Subscribed
A systematic chemical investigation of the deep-sea-derived fungus Penicillium limosum ZEN48 resulted in the isolation of four new indole-diketopiperazine alkaloids, limopiperazines A–D ( 1 – 4 ), alongside 16 known analogues ( 5 – 20 ). The structures of the new compounds were determined through comprehensive spectroscopic analysis, quantum chemical calculations, X-ray crystallography, and biogenetic considerations. Limopiper...