During liver injury, early pathological changes may go unnoticed, delaying the diagnosis until the disease has advanced to stages such as fibrosis, cirrhosis, or hepatocellular carcinoma. Hepatic fibrosis is a sign of long-term liver injury that leads toward permanent liver damage. It involves the buildup of too much extracellular matrix (ECM) and is activated by hepatic stellate cells (HSCs). The transforming growth factor-β1...

In this study, a new double-moment warm rain Goddard 4ICE scheme (GCEDM) is developed based on the Goddard 4ICE single-moment (GCESM) scheme and then tested using idealized 2D squall line and 3D supercell simulations. The addition of the total number concentrations for cloud water ( $$\:{N}_{TC}$$ ) and rainwater ( $$\:{N}_{TR}$$ ) enables this new scheme to simulate more diverse raindrop size distributions, making it more rea...