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Springer Nature1
Journal
Archives of Toxicology1
Publication Year
20211
Claudius Pak results 1 · Newest (Page 1/1, per page 25)
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Systems toxicology study reveals reduced impact of heated tobacco product aerosol extract relative to cigarette smoke on premature aging and exacerbation effects in aged aortic cells in vitroNARA Subscribed
Archives of Toxicology · 2021 · Vol. 95 · Issue 10 · Springer
Carine Poussin; Marco van der Toorn; Sophie Scheuner; Romain Piault; Athanasios Kondylis; Rebecca Savioz; Rémi Dulize; Dariusz Peric; Emmanuel Guedj; Fabio Maranzano; Celine Merg; Moran Morelli; Anne-Laure Egesipe; Stéphanie Johne; Shoaib Majeed; Claudius Pak; Thomas Schneider; Walter K. Schlage; Nikolai V. Ivanov; Manuel C. Peitsch; Julia Hoeng
Aging and smoking are major risk factors for cardiovascular diseases (CVD). Our in vitro study compared, in the context of aging, the effects of the aerosol of Tobacco Heating System 2.2 (THS; an electrically heated tobacco product) and 3R4F reference cigarette smoke (CS) on processes that contribute to vascular pathomechanisms leading to CVD. Young and old human aortic smooth muscle cells (HAoSMC) were exposed to various conc...
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