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Parasites play a critical yet understudied role in Arctic ecosystems, particularly within key subsistence species such as Arctic char ( Salvelinus alpinus ). As the Arctic undergoes rapid climate-driven change, establishing baseline parasite biodiversity is essential for monitoring ecological shifts and anticipating emerging health and conservation concerns. This study provides the most comprehensive assessment to date of Arct...
The role of MEGF10 in myoblast fusion and hypertrophic response to overload of skeletal muscleNARA Subscribed
Biallelic mutations in multiple EGF domain protein 10 ( MEGF10 ) gene cause EMARDD (early myopathy, areflexia, respiratory distress and dysphagia) in humans, a severe recessive myopathy, associated with reduced numbers of PAX7 positive satellite cells. To better understand the role of MEGF10 in satellite cells, we overexpressed human MEGF10 in mouse H-2k b -tsA58 myoblasts and found that it inhibited fusion. Addition of purifi...
The ciliary marginal zone (CMZ) is a region in the peripheral-most retina that displays ongoing retinogenesis during growth and expansion of the eye in adulthood. While there is evidence that this capacity also exists in birds and mammals, it is far more robust in fish and amphibians. The process of CMZ retinogenesis is essentially equivalent to that seen early in the central retina; however, its regulation is not fully unders...
Product repair in a circular economy: Exploring public repair behavior from a systems perspectiveNARA Subscribed
Repair practices are driven not only by consumers’ internal motivation, but also by external infrastructural, social including cultural, financial, and political factors. We explore these factors with the goal of understanding the public repair of electrical and electronic products (e‐products) from a systems perspective to help devise appropriate change interventions. We document (a) behavioral aspects, (b) techno‐economic fa...