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Psychopharmacology · 2023 · Vol. 240 · Issue 5 · Springer
Rationale The endocannabinoid system makes critical contributions to reward processing, motivation, and behavioral control. Repeated exposure to THC or other cannabinoid drugs can cause persistent adaptions in the endocannabinoid system and associated neural circuitry. It remains unclear how such treatments affect the way rewards are processed and pursued. Objective and methods We examined if repeated THC exposure (5 mg/kg/day...