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NARA Subscribed1
Publisher
Springer Nature1
Journal
Drug Delivery and Translational Research1
Publication Year
20221
Concetta Avitabile results 1 · Newest (Page 1/1, per page 25)
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Biodegradable nanoparticles combining cancer cell targeting and anti-angiogenic activity for synergistic chemotherapy in epithelial cancerNARA Subscribed
Drug Delivery and Translational Research · 2022 · Vol. 12 · Issue 10 · Springer
Francesca Moret; Claudia Conte; Diletta Esposito; Giovanni Dal Poggetto; Concetta Avitabile; Francesca Ungaro; Natascia Tiso; Alessandra Romanelli; Paola Laurienzo; Elena Reddi; Fabiana Quaglia
A biodegradable engineered nanoplatform combining anti-angiogenic activity and targeting of cancer cells to improve the anticancer activity of docetaxel (DTX) is here proposed. Indeed, we have developed biodegradable nanoparticles (NPs) of poly(ethylene glycol)-poly(ε-caprolactone), exposing on the surface both folate motifs (Fol) for recognition in cells overexpressing Folate receptor-α (FRα) and the anti-angiogenic hexapepti...
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