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Fungi have been extensively studied for their capacity to biotransform a wide range of natural and xenobiotic compounds. This versatility is a reflection of the broad substrate specificity of fungal enzymes such as laccases, peroxidases and cytochromes P450, which are involved in these reactions. This review gives an account of recent advances in the understanding of fungal metabolism of drugs and pollutants such as dyes, agro...
Enhanced removal of perfluorooctanoic acid with sequential photocatalysis and fungal treatmentNARA Subscribed
In this paper, we report the degradation of perfluorooctanoic acid (PFOA), which is a persistent contaminant in the environment that can severely impact human health, by exposing it to a photocatalyst, bismuth oxyiodide (BiOI), containing both Bi 4 O 5 I 2 and Bi 5 O 7 I phases and a fungal biocatalyst ( Cunninghamella elegans ). Individually, the photocatalyst (after 3 h) and biocatalyst (after 48 h) degraded 35–40% of 100 pp...
Environmental or occupational exposure of humans to trichloroethylene (TCE) has been associated with different extrahepatic toxic effects, including nephrotoxicity and neurotoxicity. Bioactivation of TCE via the glutathione (GSH) conjugation pathway has been proposed as underlying mechanism, although only few mechanistic studies have used cell models of human origin. In this study, six human derived cell models were evaluated...
Drug metabolism in microorganismsNARA Subscribed
Microbial biotransformation of aryl sulfanylpentafluoridesNARA Subscribed
An isotopic labeling method for determining production of volatile organohalogens by marine microalgaeNARA Subscribed
An isotopic method has been developed to establish the biological production of volatile organohalogens. The marine microalgae Porphyridium purpureum and Dunaliella tertiolecta were grown in seawater medium containing NaH 13 CO 3 , and volatile organohalogens were extracted and analyzed by gas chromatography‐mass spectrometry (GC‐MS). Isotopically labeled methyl halides were formed in each microalgal culture, and the 13 CHCl 3...
Peroxidases from marine microalgaeNARA Subscribed
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