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Total plasma N-glycomic patterns of COVID-19 diseaseNARA Subscribed
Total plasma N -glycans alter in disease states, with few studies focused on COVID-19. A discovery cohort of 310 COVID-19 patients, replicated with 97 COVID-19 patients and tested with 100 COVID-19 patients, was used to unearth the N -glycans capable of distinguishing infection, as well as prognosis of intensive care unit (ICU) admission and mortality. All significant bisected glycans were decreased in patients compared to con...
Improving inferences from coyote (Canis latrans) surveys across Illinois using integrated state-space modelsNARA Subscribed
Anthropogenic influences on landscapes changed wildlife communities immensely over the last century. One notable example of human-derived change is the expansion of coyote ( Canis latrans ) populations following the extirpation of apex carnivores and the inception of industrial agriculture in North America. In Illinois, USA, the Department of Natural Resources estimates relative abundance of coyotes using a variety of survey t...
Body Size Decline in an Endangered Bat Is Associated With Climate Change at a Continental Scale but Varies by Phenophase and RegionNARA Subscribed
At high latitudes, hibernating species must replenish their energy reserves within a 4–6 month active season. During this window, insectivorous bats at higher latitudes must consume sufficient arthropod prey to support reproduction and migration, despite suboptimal weather and prey abundance that varies across time and space. Local declines in body size of endangered little brown bats ( Myotis lucifugus ) suggest ongoing nutri...
The hyperiid amphipod Brachyscelus rapacoides is a warm-water species associated with gelatinous zooplankton. In the Mediterranean it has been reported in association with Rhopilema nomadica in both Israel and Turkey. Here, we document the first record of B. rapacoides in Greek waters, representing the first confirmed record for Europe, based on both morphological examination and DNA barcoding of the mitochondrial COI gene. Sp...
Interlaboratory clinical chemistry parameter variation in seven-day acute hydrazine toxicity studies in the Sprague-Dawley ratNARA Subscribed
Clinical chemistry retains its position as a cornerstone of toxicological assessment, yet inter-laboratory variability in baseline values remains a challenge for the integration and interpretation of multisite datasets. This study leveraged a publicly available clinical chemistry database to assess the impact of inter-laboratory variability in response to hydrazine-induced steatosis. Seventeen clinical chemistry and physico-ch...
Despite their potential to inform sustainable regional harvest and climate‐resilient fisheries management, spatial stock assessment models remain underused for management advice. To identify barriers that inhibit broader use of these methods, we conducted a blinded international simulation experiment mimicking real‐world stock assessment development when confronting spatial complexity. Seven analyst teams built spatially aggre...
Background Triazoles are widely used for treatment and prevention of invasive aspergillosis (IA) but can cause serious drug-drug interactions (DDIs) with chemotherapeutic (CT) and immunosuppressant (IS) agents via CYP3A4 inhibition. The frequency of triazole-CT or IS concurrent administration in hematologic malignancies (HM) patients newly admitted with IA is largely unknown. Methods We studied US IQVIA claims including adults...
Recent insect declines have raised global concern, but assessing insect population trends remains challenging due to limited long‐term monitoring data. Understanding the timing of population changes is essential for discerning the relative impacts of drivers like land use modification and climate change. Importantly for conservation, species that have undergone recent declines should ideally also be distinguished from species...
Terrigenous inputs link nutrient dynamics to microbial communities in a tropical lagoonNARA Subscribed
Nutrient availability drives community structure and ecosystem processes, especially in tropical lagoons that are typically oligotrophic but often receive allochthonous inputs from land. Terrestrially derived nutrients are introduced to tropical lagoons by surface runoff and submarine groundwater discharge, which are influenced by seasonal precipitation. However, terrigenous inputs presumably diminish along the onshore–offshor...
Efficient Burial of Labile Organic Carbon in Sediments of Oxygenated Icelandic FjordsNARA Subscribed
Fjords are hotspots of organic carbon (OC) burial, making them key components in the global carbon cycle. Recent research shows high marine OC burial even under oxic fjord water columns, broadening the scope of key drivers of OC burial therein. Here, we investigate the fate of marine OC in fjord sediments underlying oxic bottom waters in East Iceland. We estimate OC sources using stable isotopes, degradation using chemical bio...