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Screening the γ-core Motif Peptides of Ascomycetous Antifungal Proteins for Antifungal Activity and Potential Therapeutic ApplicabilityNARA Subscribed
The incidence of fungal infections has increased markedly in recent years, driven by increasing resistance to conventional antifungal agents. To address this challenge, the World Health Organization has highlighted the urgent need for novel antifungal molecules, particularly those that can enhance the efficacy of existing drugs. Synthetic peptides (γAFPs), derived from conserved γ-core motifs (GXC-X 3 − 9 -C) of antifungal pro...
In 2024 and 2025, leaf spot symptoms were observed in a jujube ( Ziziphus jujuba ) cultivar collection in Hungary. The symptoms manifested as small, brown necrotic spots, a few millimetres in diameter, surrounded by a chlorotic margin, resembling to Alternaria leaf spot. The pathogen was successfully isolated from symptomatic leaves, and was identified as a member of the Alternaria arborescense species complex through morpholo...
Aortic stenosis (AS) is the most prevalent valve disease in developed countries, with its incidence rising in the aging population. The current criteria for aortic valve replacement (AVR) are based on subjective symptoms and left ventricular ejection fraction (LVEF), which may not adequately reflect left ventricular (LV) dysfunction. This highlights the necessity for objective biomarkers to evaluate subclinical LV dysfunction....
Aortic stenosis has become the most prevalent valvular disease with increasing life expectancy and the ageing of the population, representing a significant clinical burden for health care providers. Its treatment has been revolutionized by transcatheter aortic valve replacement (TAVR) as a safe and minimally invasive option for elderly patients. Left ventricular (LV) functional measurement is of particular importance before TA...
Plant pathogenic fungi are responsible for enormous crop losses worldwide. Overcoming this problem is challenging as these fungi can be highly resistant to approved chemical fungicides. There is thus a need to develop and introduce fundamentally new plant and crop protection strategies for sustainable agricultural production. Highly stable extracellular antifungal proteins (AFPs) and their rationally designed peptide derivativ...
Hybridization associated with polyploidization and apomixis is a frequent mechanism of speciation. Sorbus is a genus with ongoing hybridization resulting in a polyploid complex with different parental lineage. Triparens is the smallest hybridogenous subgenus of Sorbus so far known to comprise only two taxa, S. intermedia and S. × liljeforsii that combine the genomes of three taxa ( S. aria agg., S. aucuparia and S. torminalis...
Novel coronavirus epidemic in the Hungarian population, a cross-sectional nationwide survey to support the exit policy in HungaryNARA Subscribed
After months of restrictive containment efforts to fight the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) epidemic, European countries are planning to reopen. To support the process, we conducted a cross-sectional survey among the Hungarian population to estimate the prevalence of infectious cases and prior SARS-CoV-2 exposure. A representative sample ( n = 17,787) for the Hungarian population of 14 years or ol...
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