Brain age, an estimate of biological brain aging derived from neuroimaging, has been linked to cognitive and related factors. Metrics such as the Brain Age Gap Estimate (BrainAGE), depicting the discrepancy between predicted and chronological age, are commonly used to determine the influence of variables on brain aging. This study explored how cognitive ability, musical sophistication, and social skills contribute to BrainAGE...

The precuneus shows considerable heterogeneity in multiple dimensions including anatomy, function, and involvement in brain disorders. Leveraging the state-of-the-art functional gradient approach, we aimed to investigate the hierarchical organization of the precuneus, which may hold promise for a unified understanding of precuneus heterogeneity. Resting-state functional MRI data from 793 healthy individuals were used to discov...