D. Batt results 18
· Newest (Page 1/1, per page 25)
Author: D. Batt ×Clear All Filters
Search Results
Focused ultrasound-mediated opening of the blood brain barrier for non-invasive drug delivery to the murine cerebellumNARA Subscribed
Background The blood brain barrier (BBB) limits effective treatment for cerebellar diseases. Region-specific parameterization and safety data for MRI-guided focused ultrasound (MRgFUS) BBB opening (BBBO) in the cerebellum are scarce. The goal of this study is to establish safety and feasibility of cerebellar BBBO for antibody delivery. Methods Mice received i.v. AF680 IgG and microbubbles immediately prior to sonication at 0.3...
Assessment of Bottom Trawl Impacts on the Status of Seabed Communities in European SeasNARA Subscribed
Bottom trawling affects seabed habitats, but its large‐scale impacts remain poorly quantified. Assessment of trawling impacts is essential to support monitoring and achieving sustainability objectives under international conventions, sustainable development goals, and seafood certification programs. We present a Europe‐wide quantitative assessment of bottom trawling impacts, accounting for regional seabed‐community sensitivity...
Prolonging survival in good health is a fundamental societal goal. However, the leading determinants of disability-free survival in healthy older people have not been well established. Data from ASPREE, a bi-national placebo-controlled trial of aspirin with 4.7 years median follow-up, was analysed. At enrolment, participants were healthy and without prior cardiovascular events, dementia or persistent physical disability. Disab...
Diversity in thermal affinity among key piscivores buffers impacts of ocean warming on predator–prey interactionsNARA Subscribed
Asymmetries in responses to climate change have the potential to alter important predator–prey interactions, in part by altering the location and size of spatial refugia for prey. We evaluated the effect of ocean warming on interactions between four important piscivores and four of their prey in the U.S. Northeast Shelf by examining species overlap under historical conditions (1968–2014) and with a doubling in CO 2 . Because b...
Species richness has long been used as an indicator of ecosystem functioning and health. Global richness is declining, but it is unclear whether sub‐global trends differ. Regional trends are especially understudied, with most focused on island regions where richness is strongly impacted by novel colonisations. We addressed this knowledge gap by testing for multi‐decade trends in species richness in nine open marine regions aro...
Even species within the same assemblage have varied responses to climate change, and there is a poor understanding for why some taxa are more sensitive to climate than others. In addition, multiple mechanisms can drive species' responses, and responses may be specific to certain life stages or times of year. To test how marine species respond to climate variability, we analyzed 73 diverse taxa off the southeast US coast in 26...
Ecology under lake iceNARA Subscribed
Winter conditions are rapidly changing in temperate ecosystems, particularly for those that experience periods of snow and ice cover. Relatively little is known of winter ecology in these systems, due to a historical research focus on summer ‘growing seasons’. We executed the first global quantitative synthesis on under‐ice lake ecology, including 36 abiotic and biotic variables from 42 research groups and 101 lakes, examining...
A Bayesian mixing model and stable isotopes of carbon, nitrogen, and hydrogen were used to evaluate the extent to which six consumers (three fishes, two zooplankton, and a snail) in a naturally productive lake used terrestrial resources, epilimnetic and metalimnetic phytoplankton, benthic algae, and macrophytes. Resource use varied with consumer habitat use and feeding ability, but allochthony was consistently low (averaging 1...
Ecosystem metabolism in a stratified lakeNARA Subscribed
Seasonal changes in rates of gross primary production (GPP), net ecosystem production (NEP), and respiration (R) were determined from frequent automated profiles of dissolved oxygen (DO) and temperature in a clear‐water polymictic lake. Metabolic rate calculations were made using a method that integrates rates across the entire depth profile and includes DO exchange between depth layers driven by mixed‐layer deepening and eddy...
To assess the risk of transmission of infectious haematopoietic necrosis virus (IHNV) associated with the movement of processed rainbow trout, Oncorhynchus mykiss , from an area where the virus is endemic, 240 freshly eviscerated fish (225–500 g) exhibiting spinal curvature or spinal compression types of deformities were tested for IHNV by virus isolation and polymerase chain reaction (PCR) techniques. Commercially produced ra...
Previous1Next