Argininosuccinate lyase (ASL) is essential for the NO-dependent regulation of tyrosine hydroxylase (TH) and thus for catecholamine production. Using a conditional mouse model with loss of ASL in catecholamine neurons, we demonstrate that ASL is expressed in dopaminergic neurons in the substantia nigra pars compacta, including the ALDH1A1 + subpopulation that is pivotal for the pathogenesis of Parkinson disease (PD). Neuronal l...

Common vampire bat populations distributed from M exico to A rgentina are important rabies reservoir hosts in Latin A merica. The aim of this work was to analyse the population structure of the rabies virus ( RABV ) variants associated with vampire bats in the Americas and to study their phylodynamic pattern within A rgentina. The phylogenetic analysis based on all available vampire bat‐related N gene sequences showed both a g...