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Identification of a novel isoform of Slc26a4 by single-cell RNA-sequencing of pendrin-expressing cells in the cochleaNARA Subscribed
Pathogenic variation of SLC26A 4 gene causes both Pendred syndrome (PDS) and non-syndromic enlarged vestibular aqueduct (NSEVA/DFNB4), two autosomal recessive disorders. The former accounts for approximately 6% of human genetic hearing loss, making it the second most common form of syndromic deafness after Usher syndrome, while the latter is the most common radiological malformation associated with childhood sensorineural hear...
Vietnam’s Mekong Delta plays a pivotal role in national and global food security. However, agriculture-based livelihoods in the delta are highly susceptible to climate extremes, highlighting the need for more localized climate change information. Hence, this study applied univariate and multivariate bias correction methods to raw climate model simulations from the Coupled Model Intercomparison Project Phase 6 under eight Share...
We describe the identification, synthesis, and field testing of an aggregation-sex pheromone produced by male Acalolepta aesthetica (Olliff 1890) (Coleoptera: Cerambycidae: Lamiinae), a cerambycid beetle native to Australia that has recently become established in Hawai‘i. Comparing extracts of headspace volatiles from both sexes revealed that males emitted two sex-specific volatiles, (3 E ,5 Z )-octadien-2-ol and (3 E ,5 Z )-o...