Climatic and evolutionary processes are inextricably linked to conservation. Avoiding extinction in rapidly changing environments often depends upon a species’ capacity to adapt in the face of extreme selective pressures. Here, we employed exon capture and high‐throughput next‐generation sequencing to investigate the mechanisms underlying population structure and adaptive genetic variation in the koala ( Phascolarctos cinereus...

Millions of Americans experience pain daily. In 2017, opioid overdose claimed 64,000 lives increasing to 84,000 lives in 2020, resulting in a decrease in national life expectancy. Chronic opioid use results in dependency, drug tolerance, neuroadaptation, hyperalgesia, potential addictive behaviors, or Reward Deficiency Syndrome (RDS) caused by a hypodopaminergia. Evaluation of pain clinic patients with the Genetic Addiction Ri...

The International Comprehensive Ocean–Atmosphere Data Set (ICOADS), release 2.1 (1784–2002), is the largest available set of in situ marine observations. Observations from ships include instrument measurements and visual estimates, and data from moored and drifting buoys are exclusively instrumental. The ICOADS collection is constructed from many diverse data sources, and made inhomogeneous by the changes in observing systems...