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Use of translational fusions to express functional Klebsiella oxytoca dinitrogenase reductase in plant mitochondriaNARA Subscribed
Engineering crop plants with the biological nitrogen fixation pathway is a longstanding goal of modern agriculture. Dinitrogenase reductase (NifH) is a critical component of the biological nitrogen fixation pathway, with multiple roles in metal cofactor assembly and catalysis. This enzyme must be folded correctly as a soluble homodimer and loaded with the [4Fe-4S] metallocluster for function. Previous studies have found that K...
Relationship of temperature with declines and persistence of Myotis lucifugus after white‐nose syndromeNARA Subscribed
White‐nose syndrome (WNS), caused by the fungus Pseudogymnoascus destructans (Pd), ranks among the most devastating wildlife diseases in recent history and is driving severe declines in North American bats. Identifying environmental factors that influence both the severity of population crashes and the potential for population persistence is essential for effective mitigation. We used a long‐term dataset from hibernacula acros...
The underrepresentation of racial and ethnic minority scientists in research is a significant barrier to eliminating cancer health disparities. There is a compelling need to develop a cadre of racially and ethnically diverse, well-trained scientists to effectively meet the nation’s biomedical, behavioral, population, and clinical cancer research needs. The Florida-California Cancer Research, Education and Engagement Health Equ...
SNAPSHOT USA 2024: Year 6 of the Coordinated National Camera Trap Survey of the United StatesNARA Subscribed
Motivation SNAPSHOT USA is an annual, multi‐contributor camera trap survey of mammals across the United States. The growing SNAPSHOT USA dataset is intended for tracking the spatial and temporal responses of mammal populations to changes in land use, land cover and climate. These data will be useful for exploring the drivers of spatial and temporal changes in relative abundance and distribution, as well as the impacts of speci...
Centering Accessibility in Food Security Resource ResearchNARA Subscribed
IND-enabling preclinical studies of [11C]COU, a trapped metabolite PET radiotracer for monoamine oxidase-BNARA Subscribed
[ 11 C]COU is a trapped metabolite radiotracer for in vivo analysis of Monoamine Oxidase B activity using positron emission tomography (PET) imaging. [ 11 C]COU has the potential to quantify astrocytosis in the early stages of Alzheimer’s disease, providing an earlier marker of disease than currently available for staging disease progression. Prior preclinical studies have demonstrated the efficacy of this radiotracer in precl...