D.J. Coetzee results 17
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Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severityNARA Subscribed
The combined impact of common and rare exonic variants in COVID-19 host genetics is currently insufficiently understood. Here, common and rare variants from whole-exome sequencing data of about 4000 SARS-CoV-2-positive individuals were used to define an interpretable machine-learning model for predicting COVID-19 severity. First, variants were converted into separate sets of Boolean features, depending on the absence or the pr...
Global genetic diversity of Aedes aegyptiNARA Subscribed
Mosquitoes, especially Aedes aegypti , are becoming important models for studying invasion biology. We characterized genetic variation at 12 microsatellite loci in 79 populations of Ae. aegypti from 30 countries in six continents, and used them to infer historical and modern patterns of invasion. Our results support the two subspecies Ae. aegypti formosus and Ae. aegypti aegypti as genetically distinct units. Ae. aegypti aegyp...
Overview of the KwaZulu-Natal sardine runNARA Subscribed
Molecular phylogeny of Armillaria from the Patagonian AndesNARA Subscribed
Rangewide population genetic structure of the African malaria vector Anopheles funestusNARA Subscribed
Anopheles funestus is a primary vector of malaria in Africa south of the Sahara. We assessed its rangewide population genetic structure based on samples from 11 countries, using 10 physically mapped microsatellite loci, two per autosome arm and the X ( N = 548), and 834 bp of the mitochondrial ND5 gene ( N = 470). On the basis of microsatellite allele frequencies, we found three subdivisions: eastern (coastal Tanzania, Malawi,...
The root rot fungus Armillaria mellea introduced into South Africa by early Dutch settlersNARA Subscribed
Dead and dying oak ( Quercus ) and numerous other woody ornamental trees and shrubs showing signs and symptoms of Armillaria root rot were identified in the Company Gardens, Cape Town, South Africa, which were established in the mid‐1600s by the Dutch East Indies Trading Company. Nineteen isolates from dying trees or from mushrooms were collected and analysed to identify and characterize the Armillaria sp. responsible for the...
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