Whether phenotypic plasticity facilitates adaptive evolution is a key question in evolutionary ecology. The discovery of limb-length plasticity in two Anolis lizard species led to hypotheses about its role in the Anolis radiation. Yet, whether limb plasticity is realized in nature and has adaptive significance is poorly understood. In this study, we combined a limb-length plasticity experiment, lab-based assays of hatchling be...

Vascular Endothelial Growth Factor A (VEGF-A) is an angiogenic signaling protein involved in the maintenance of the cerebral vasculature. No prior study has explored whether plasma VEGF-A levels may be associated with brain functional connectivity changes, such as disruption of the default mode network (DMN), which often precedes the development of cognitive changes in aging. Seventy-six independently living older adults (mean...

Visit-to-visit blood pressure variability (BPV) predicts age-related hippocampal atrophy, neurodegeneration, and memory decline in older adults. Beat-to-beat BPV may represent a more reliable and efficient tool for prospective risk assessment, but it is unknown whether beat-to-beat BPV is similarly associated with hippocampal neurodegeneration, or with plasma markers of neuroaxonal/neuroglial injury. Independently living older...