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Purpose Systematic collection and analysis of antimicrobial resistance data from key bacterial pathogens is essential to contribute to control antimicrobial resistance (AMR). The aim of this work was to survey the drug resistance on clinically relevant organisms stratified according to age, gender, clinical specimens and facilities. Methods Microbiological data were collected from 55 centers across 24 states in Mexico between...
Cortical volumetry and longitudinal cognitive changes in Parkinson’s disease: insights from the COPPADIS cohortNARA Subscribed
Cognitive decline is a major non-motor symptom in Parkinson’s disease (PD), often linked to brain atrophy. This study examines the relationship between cortical atrophy and age groups in predicting cognitive decline in PD over five years. 188 PD patients from the COPPADIS cohort were stratified by age: young (30–55 years, N = 47), middle-aged (56–65 years, N = 59), and older adults (66–75 years, N = 82). Baseline cortical volu...
Chromosome-Y haplogroups in Asturias (Northern Spain) and their association with severe COVID-19NARA Subscribed
The main objective of this study was to determine whether the common Y-haplogroups were be associated with the risk of developing severe COVID-19 in Spanish male. We studied 479 patients who required hospitalization due to COVID-19 and 285 population controls from the region of Asturias (northern Spain), They were genotyped for several polymorphisms that define the common European Y-haplogroups. We compared the frequencies bet...
Mesoscale eddies cause deviations from the background physical and biogeochemical states of the oligotrophic oceans, but how these perturbations manifest in microbial ecosystem functioning, such as community macromolecular composition or carbon export, remains poorly characterized. We present comparative lipidomes from communities entrained in two eddies of opposite polarities (cyclone–anticyclone) in the North Pacific Subtrop...
Immunoglobulin genes and severity of COVID-19NARA Subscribed
There is tremendous interindividual and interracial variability in the outcome of SARS-CoV-2 infection, suggesting the involvement of host genetic factors. Here, we investigated whether IgG allotypes GM (γ marker) 3 and GM 17, genetic markers of IgG1, contributed to the severity of COVID-19. IgG1 plays a pivotal role in response against SARS-CoV-2 infection. We also investigated whether these GM alleles synergistically/epistat...
With an estimated theoretical resource of over 30,000 TWh/yr [...]
This paper discusses a disruptive approach to wave energy conversion, based on a hybrid solution: the E-Motions wave energy converter with integrated triboelectric nanogenerators. To demonstrate it, a physical modelling study was carried out with nine E-Motions sub-variants, which were based on three original hull designs (half-cylinder (HC), half-sphere (HS) and trapezoidal prism (TP)). A unidirectional lateral tribo-device w...
Hydraulic and Structural Assessment of a Rubble-Mound Breakwater with a Hybrid Wave Energy ConverterOA Marine
Seaports’ breakwaters serve as important infrastructures capable of sheltering ships, facilities, and harbour personnel from severe wave climate. Given their exposure to ocean waves and port authorities’ increasing awareness towards sustainability, it is important to develop and assess wave energy conversion technologies suitable of being integrated into seaport breakwaters. To fulfil this goal whilst ensuring adequate shelter...