Total plasma N -glycans alter in disease states, with few studies focused on COVID-19. A discovery cohort of 310 COVID-19 patients, replicated with 97 COVID-19 patients and tested with 100 COVID-19 patients, was used to unearth the N -glycans capable of distinguishing infection, as well as prognosis of intensive care unit (ICU) admission and mortality. All significant bisected glycans were decreased in patients compared to con...

Residual herbicides are widely used in weed management; however, their persistence in the environment can lead to agronomic and ecological impacts. This study assessed bacterial isolates obtained from sugarcane soil with a history of diuron exposure for their ability to increase diuron dissipation under controlled conditions. Forty-two bacterial isolates were obtained, of which 18 tolerated the commercial formulation at 1,000...

The present study aimed to comprehensively characterize the cancer-associated virome in patients with gastric cancer. A total of 452 samples were analyzed, including 226 tumor tissues and 202 peritumoral tissues from patients undergoing surgical resection, alongside 24 normal gastric mucosa samples obtained via endoscopy from individuals without cancer. RNA was extracted, libraries were prepared, and paired-end sequencing was...

This study evaluated the reliability of functional data imputed in the classification of ecological strategies according to the CSR model (competitive, stress-tolerant, ruderal) in tree species of a riparian Atlantic Forest in Brazil. Empirical data collected in situ from 68 species were compared with data imputed using the Bayesian Hierarchical Probabilistic Matrix Factorization (BHPMF) technique, considering key functional a...

Estuarine fishes experience marked environmental variability and rely on tightly regulated osmoregulatory mechanisms to maintain internal homeostasis. Settleable atmospheric particulate matter (SePM), a complex mixture of metals and metalloids, is an emerging stressor in aquatic systems and may interfere with regulatory processes. This study investigated the effects of SePM exposure on osmoregulatory homeostasis in the estuari...

Accurate detection of high-risk human papillomavirus (HPV) is central to cervical cancer screening. Current diagnostic strategies increasingly prioritize broad-spectrum assays to maximize genotype coverage. However, theoretical genotype breadth does not necessarily translate into effective sample-level detection when clinically dominant targets are present at low copy number. Here, we evaluated this analytical trade-off using...

Purpose Vascular dysfunction is a pathophysiological mechanism in peripheral artery disease (PAD). PAD patients exhibit reduced circulating expression of microRNA-126 (c-miRNA-126) and VEGF. Submaximal walking (SW) is recommended in PAD because it increases walking capacity, partially by improving vascular regulation, which can be observed after a walking session. Nevertheless, previous studies were conducted with maximal walk...

The commerce of decorative dried plants from the Brazilian Cerrado Biome provides cultural transmission, and essential revenue for low-income families. We investigated this production value chain over the past decade, assessing its economic and social relevance and mapping the main actors involved, and characterizing the interviewed participants, as well as the foreign trade trends over 50 years. Data was gathered through inte...