Crop diversification is a promising strategy to strengthen pest control services in agricultural landscapes. Diversifying crops may limit pests through host crop dilution or by enhancing top‐down control by their enemies. However, crop diversification may also benefit generalist pests through higher resource continuity. Using a large‐scale dataset encompassing 742 landscapes across 13 countries, we assessed the impact of lands...

Land‐use change has altered the composition of our landscapes to favour agriculture, negatively affecting biodiversity and ecosystem services. However, the links between landscape composition, pest control and yield remain unclear. Using a global structural equation model of 116 studies from 28 countries, we tested three hypotheses: the ‘natural enemy hypothesis’, that natural areas increase natural enemies and suppress pests;...

Bioerosion plays a crucial factor in shaping the structure and function of coral reef ecosystems, with bioeroders actively altering both the physical and ecological dynamics of coral substrates. Despite their importance, studying internal bioeroders in corals presents significant challenges owing to their cryptic nature within the skeletal structures. Additionally, invasive methods are often required to reveal the subtle and m...

Epigenetic aging clocks are computational models that predict age using DNA methylation information. Initially, first-generation clocks were developed to make predictions using CpGs that change with age. Over time, next-generation clocks were created using CpGs that relate to both age and health. Since existing next-generation clocks were constructed in blood, we sought to develop a next-generation clock optimized for predicti...

The determination of a tailored anti-drug antibody (ADA) testing strategy is based on the immunogenicity risk assessment to allow a correlation of ADAs with changes to pharmacokinetics, efficacy, and safety. The clinical impact of ADA formation refines the immunogenicity risk assessment and defines appropriate risk mitigation strategies. Health agencies request for high-risk biotherapeutics to extend ADA monitoring for patient...

Coastal zones, which connect terrestrial and aquatic ecosystems, are among the most resource‐rich regions globally and home to nearly 40% of the global human population. Because human land‐based activities can alter natural processes in ways that affect adjacent aquatic ecosystems, land‐sea interactions are increasingly recognized as critical to coastal conservation planning and governance. However, the complex socioeconomic d...

Evolving immunogenicity assay performance expectations and a lack of harmonized anti-drug antibody validation testing and reporting tools have resulted in significant time spent by health authorities and sponsors on resolving filing queries. Following debate at the American Association of Pharmaceutical Sciences National Biotechnology Conference, a group was formed to address these gaps. Over the last 3 years, 44 members from...

Neuroscience incorporates knowledge from a range of scales, from single molecules to brain wide neural networks. Modeling is a valuable tool in understanding processes at a single scale or the interactions between two adjacent scales and researchers use a variety of different software tools in the model building and analysis process. Here we focus on the scale of biochemical pathways, which is one of the main objects of study...

Summary Acetogenic bacteria are already established as biocatalysts for production of high‐value compounds from C1 substrates such as H 2 + CO 2 or CO. However, little is known about the physiology, biochemistry and bioenergetics of acetogenesis from formate, an interesting feedstock for biorefineries. Here, we analysed formate metabolism in the model acetogen Acetobacterium woodii . Cells grew optimally on 200 mM formate to a...

Motivation Trait data are fundamental to the quantitative description of plant form and function. Although root traits capture key dimensions related to plant responses to changing environmental conditions and effects on ecosystem processes, they have rarely been included in large‐scale comparative studies and global models. For instance, root traits remain absent from nearly all studies that define the global spectrum of plan...

Diversifying agricultural landscapes may mitigate biodiversity declines and improve pest management. Yet landscapes are rarely managed to suppress pests, in part because researchers seldom measure key variables related to pest outbreaks and insecticides that drive management decisions. We used a 13‐year government database to analyse landscape effects on European grapevine moth ( Lobesia botrana ) outbreaks and insecticides ac...