The CRISPR-Cas13 system has emerged as a powerful platform for programmable RNA targeting, offering efficient and sequence-specific silencing of coding and non-coding transcripts. The RNA-targeting capabilities of CRISPR-Cas13 have been harnessed to silence transcripts harbouring pathogenic mutations and combat infectious diseases. However, the molecular basis of on-target and collateral activity are not completely understood,...

The Archean Legris Lake mafic–ultramafic complex (LLC) is spatially (~ 12 km east) and temporally (2690.59 ± 0.77 Ma) associated with the world-class Lac des Iles (LDI) palladium deposit. Modeling of whole-rock major-element compositions suggests that this complex, previously interpreted as gabbroic, is gabbronoritic in composition, adding to the likely association between LDI and the LLC. Mantle normalized trace-element profi...

Polymorphic species are useful models for investigating the evolutionary processes driving diversification. Such processes include colonization history as well as contemporary selection, gene flow, and genetic drift, which can vary between intraspecific morphs as a function of their distinct life histories. The interactive and relative influence of such evolutionary processes on morph differentiation critically informs morph‐s...

Ecosystem-based conservation that includes carbon sinks, alongside a linked carbon credit system, as part of a nature-based solution to combating climate change, could help reduce greenhouse gas levels and therefore the impact of their emissions. Blue carbon habitats and pathways can also facilitate biodiversity retention, aiding sustainable fisheries and island economies. However, robust blue carbon research is often limited...

The post‐glacial colonization of Gander Lake in Newfoundland, Canada, by Arctic Charr ( Salvelinus alpinus) provides the opportunity to study the genomic basis of adaptation to extreme deep‐water environments. Colonization of deep‐water (>50 m) habitats often requires extensive adaptation to cope with novel environmental challenges from high hydrostatic pressure, low temperature, and low light, but the genomic mechanisms under...

The genetic underpinnings of incipient speciation, including the genomic mechanisms which contribute to morphological and ecological differentiation and reproductive isolation, remain poorly understood. The repeated evolution of consistently, phenotypically distinct morphs of Arctic Charr ( Salvelinus alpinus ) within the Quaternary period offer an ideal model to study the repeatability of evolution at the genomic level. Sympa...