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The increase in fungal infections, the limited therapeutic arsenal, and the emergence of resistance pose a global health problem. Candida spp. stand out as opportunistic pathogens that cause superficial and invasive diseases. Thus, the search for new therapeutic alternatives, such as drug repositioning, is necessary. Duloxetine (DUL), a serotonin-norepinephrine reuptake inhibitor antidepressant used to treat depression, has de...
Respiration Patterns of Southern Right Whale ( Eubalaena australis ) Mothers and Calves in Southern BrazilNARA Subscribed
Respiration is a key physiological process in cetaceans, closely linked to energy expenditure, behavior, and physiological state. Using drone‐based surveys, we quantified respiration patterns of southern right whale ( Eubalaena australis ) mother–calf pairs in southern Brazil across two reproductive seasons (2020–2021). Based on over 100 h of observation from 43 identified pairs, we found marked differences between classes: re...
Bioprospecting Chromobacterium violaceum for bioremediation: an alternative to environmental lead pollutionNARA Subscribed
Lead pollution is a major environmental concern, but current decontamination technologies remain limited due to high costs. Therefore, alternative biotechnological processes have been successfully developed and applied due to their reduced cost and lower aggressiveness in the environment. The remarkable adaptive versatility of Chromobacterium violaceum in metal-contaminated environments makes this bacterium a promising candida...
Optimizing maize–Brachiaria intercropping requires effective weed management with selective maize herbicides. This study evaluated the spray performance and efficacy of atrazine + nicosulfuron for weed management in maize–Brachiaria intercropping, focusing on how droplet classes and spray volumes affect maize growth and yield. The deposition experiment was conducted in a greenhouse in a completely randomized design with six re...
Type-specific sensitivity versus detection breadth in HPV diagnostics: improved analytical detection of HPV16/18 by nested PCRNARA Subscribed
Accurate detection of high-risk human papillomavirus (HPV) is central to cervical cancer screening. Current diagnostic strategies increasingly prioritize broad-spectrum assays to maximize genotype coverage. However, theoretical genotype breadth does not necessarily translate into effective sample-level detection when clinically dominant targets are present at low copy number. Here, we evaluated this analytical trade-off using...