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European Journal of Clinical Microbiology & Infectious Diseases · 2026 · Vol. 45 · Issue 5 · Springer
Purpose The DANFLU-1 trial suggested lower incidence of hospitalizations for pneumonia and influenza, respiratory disease and all-cause mortality among older adults receiving high-dose (HD-IV) versus standard-dose (SD-IV) influenza vaccine. This study assessed the relative effectiveness of HD-IV versus SD-IV according to comorbidity in elderly individuals. Methods This was a post-hoc analysis of the DANFLU-1 randomized control...