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Building climate-smart fisheries in Australia: insights from climate and ecosystem status reportsNARA Subscribed
Ongoing concerns about the impact of climate change on Australia’s oceans has driven a request from fisheries managers for improved science communication to the seafood sector. Despite these concerns, translating climate science into management and industry action at regional and sectoral scales remains a challenge. We developed a reporting structure for communicating climate and ecosystem status to fisheries management, indus...
Remote sensing and GIS-based mapping of tree fall risk and hazard along railway lines in GermanyNARA Subscribed
Trees located along railway corridors pose a significant risk to transport infrastructure, particularly in the context of increasingly frequent and intense storm events driven by climate change. Proactive vegetation management strategies are therefore essential for reducing the risk of disruptions caused by falling trees. This study applies an existing GIS-based assessment framework to analyse tree fall risk and hazard along r...
EEG-ECeG Coherence Mapping of Human Cerebro-cerebellar Projections: An Exploratory StudyNARA Subscribed
The cerebellar and cerebral cortices are powerfully connected via reciprocal, crossed projections which mediate their coordination in motor, cognitive and affective processes. In the present paper we demonstrate non-invasive imaging of crossed cerebro-cerebellar connectivity by means of wavelet coherence. In a sample of six healthy adult subjects, we recorded EEG and the electro-cerebellogram (ECeG) with a 10% cerebellar exten...
Lynch syndrome caused by a pathogenic SINE-VNTR-Alu (SVA) insertion in MSH2 gene identified by long-read DNA sequencingNARA Subscribed
Lynch syndrome, the most common hereditary cancer syndrome, is caused by germline pathogenic variants in DNA mismatch repair (MMR) genes. Identifying complex or structural MMR gene pathogenic variants can be challenging with short-read sequencing resulting in patients with unexplained MMR-deficient tumours. In this study, we report multiple members of a family who developed MSH2-deficient tumours where clinical multi-gene pane...
TEAD inhibitor induced switch in energy metabolism drives human podocyte injury in vitroNARA Subscribed
Early detection and understanding of the potential adverse effects of a drug candidate is of utmost importance to reduce the attrition rate during drug development while delivering safe medications to patients. The kidney is one of the most frequently challenged organs involved in drug-induced toxicity, including general glomerulopathy and podocyte- specific cytotoxicity with ensuing overt proteinuria. Whilst TEAD inhibitors a...
The escalating frequency and severity of marine heatwaves are driving factors behind mass coral bleaching, necessitating both rapid emission reductions and the development of scalable intervention tools. Shading coral to reduce irradiance stress is a promising approach, yet most studies focus on static structures, and few include recovery dynamics. Here, we tested the efficacy of a laboratory-scale seawater fogging system as a...