Feeding the largest share of the global population, cereal production must enhance sustainability while ensuring food security under global change. Unfortunately, the number of sustainable practices needed to support production, ecosystem services and land conservation remains virtually unknown. We compiled a database of 1570 observations from 349 sites in 57 countries to assess how the number of sustainable practices influenc...

A fossil mysticete was discovered along the southwestern coast of Spain, occurring in a block detached from the Neogene deposits exposed along a coastal cliff at the locality of Conil de la Frontera (Cádiz, Spain). These deposits range from Pliocene to Pleistocene in age and include shallow-marine, mixed carbonate–siliciclastic sediments, with the whale being found in occurrence of a stratigraphic unconformity marked by Thalas...

Rationale Major depressive disorder (MDD) is a leading cause of disability worldwide but currently prescribed treatments do not adequately ameliorate the disorder in a significant portion of patients. Hence, a better appreciation of its aetiology may lead to the development of novel therapies. Objectives In the present study, we have built on our previous findings indicating a role for protease-activated receptor-2 (PAR2) in s...