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Prospective phenotyping of CHAMP1 disorder indicates that coding mutations may not act through haploinsufficiencyNARA Subscribed
CHAMP1 disorder is a genetic neurodevelopmental condition caused by mutations in the CHAMP1 gene that result in premature termination codons. The disorder is associated with intellectual disability, medical comorbidities, and dysmorphic features. Deletions of the CHAMP1 gene, as part of 13q34 deletion syndrome, have been briefly described with the suggestion of a milder clinical phenotype. To date, no studies have directly ass...
The capacity for aquaculture to provide an alternative source of fish and seafood to capture fisheries was once promoted as a tool to reduce demand for wild fish and thus tackle overfishing. To date, there is little evidence to suggest that aquaculture growth has successfully reduced fishing effort on wild populations. Recent theory on “blue transitions” suggests that displacement may only occur as aquaculture production surpa...
The long and narrow path for novel cell‐based seafood to reduce fishing pressure for marine ecosystem recoveryNARA Subscribed
Cell‐based seafood is an emerging novel food, with many start‐up companies aspiring for ocean conservation benefits through expanded market share that displaces wild‐caught seafood. However, the ability for cell‐based seafood to achieve this conservation outcome is often oversimplified and will rely on an extensive, and we find somewhat tenuous, chain of events. Here, we outline the technological, behavioural, market and ecolo...
Effective management of aquatic resources, wild and farmed, has implications for the livelihoods of dependent communities, food security, and ecosystem health. Good management requires information on the status of harvested species, yet many gaps remain in our understanding of these species and systems, in particular the lack of taxonomic resolution of harvested species. To assess these gaps we compared the occurrence of lande...
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