Neuropathic pain arises from a primary lesion or disease affecting the somatosensory system; however, the brain circuitry underlying the regulation of neuropathic pain remains unclear. The red nucleus (RN) is a critical brain region involved in regulating muscle tension, coordinating movement, and facilitating sensorimotor integration. While some evidence has shown that RN regulates pain, its specific role in neuropathic pain...

Traumatic brain injury (TBI) causes lasting neurological impairments, particularly learning and memory deficits associated with hippocampal damage. Emerging evidence suggests that hippocampal vulnerability may be linked to bioenergetic dysfunction, though its role remains poorly defined. A deeper understanding of post-TBI metabolic disturbances and their association with pathological outcomes could reveal novel therapeutic tar...

Key message Association analysis for ionomic concentrations of 20 elements identified independent genetic factors underlying the root and shoot ionomes of rice, providing a platform for selecting and dissecting causal genetic variants. Abstract Understanding the genetic basis of mineral nutrient acquisition is key to fully describing how terrestrial organisms interact with the non-living environment. Rice ( Oryza sativa L.) se...