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Environmental Microbiology · 2021 · Vol. 23 · Issue 12 · Wiley
Summary The fitness cost of antibiotic resistance is a crucial factor to determine the evolutionary and transmission success of resistant bacteria. Exploring the fitness cost and compensation mechanism of antibiotic resistance genes (ARGs) in bacteria may effectively reduce the transmission of drug‐resistant genes in the environment. Engineered bacteria with the same genetic background that carry sulfonamide resistance gene we...