Antibody–drug conjugates (ADCs) represent a rapidly evolving therapeutic modality, combining the selective targeting of monoclonal antibodies with highly potent small molecule payloads. Their inherent structural complexity demands a sophisticated and multi-faceted bioanalytical approach spanning preclinical discovery through late-stage clinical development. This white paper, developed by the ADC Working Group of the AAPS bioan...

The isotopic composition of atmospheric carbon dioxide (δ 13 C atm ) provides insights into the terrestrial carbon cycle. However, long‐term global δ 13 C atm maps with both high spatial resolution and continuous temporal coverage remain scarce. Here, we present a new global terrestrial dataset of monthly δ 13 C atm isoscapes from 2001 to 2020 at 0.05° spatial resolution, developed by integrating in situ observations with opti...

Distributed optical fibre sensing (DOFS) is a technology that enables continuous, real-time measurements of a range of environmental parameters along the length of a fibre optic cable. In this article, we review the recently emerged applications of DOFS techniques in physical oceanography and offer a perspective on the technology's potential for future growth within the field. The introduction of DOFS to physical oceanography...

Aim Quantitative linkage between surface pollen relative abundance (RA) and source‐plant distribution is fundamental for fossil‐based vegetation and climate reconstructions. However, how phytogeographical patterns are translated into sedimentary pollen records under the extreme high‐altitude environments of the Tibetan Plateau (TP) remains a critical yet poorly understood issue. Here we integrate 3352 unique surface pollen spe...

During an investigation of Leotiomycetes in a tropical area of Yunnan Province, China, eight saprobic samples were collected from decayed wood and fallen leaves. Based on morphological and phylogenetic evidence from the dataset of partial nuclear 28S rDNA D1‐D2 regions (nLSU) and the nuclear rDNA internal transcribed spacer region ITS1‐5.8S‐ITS2 (ITS), three new species of Nagrajchalara (Pezizellaceae, Helotiales) were identif...