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BCL-2 family dysregulation in HTLV-1 and BLV pathogenesis and its implications for leukemogenesis and therapyNARA Subscribed
The B-cell Lymphoma 2 (BCL-2) family of proteins plays a fundamental role in maintaining the balance between cell survival and apoptosis, processes that are frequently manipulated by oncogenic viruses. This review explores the contribution of BCL-2 family members to the pathogenesis of deltaretroviruses, with emphasis on Human T-cell Leukemia Virus type 1 (HTLV-1) and Bovine Leukemia Virus (BLV). Both viruses employ viral onco...
Providing regular and frequent maps of losses and gains of farmland birds based on European monitoring dataNARA Subscribed
Knowledge of species distributions is essential for informing policies on nature conservation and restoration. However, updating them on a regular basis and doing so in a harmonized manner at the international level is difficult. The European Bird Census Council integrated national monitoring data covering 5 years to update farmland bird distributions and assessed how they changed. We used these data on 50 farmland bird specie...
Spontaneous juggling behavior in a wild urban capuchin monkey (Sapajus nigritus cucullatus)NARA Subscribed
Juggling, defined as the repeated and rhythmic throwing and catching of an object, is a rare and complex form of object manipulation among non-human animals. While object play has been described in several taxa, true juggling behavior, intentional, successive aerial manipulation of the same object, has only been formally documented in a few species such as otters, dolphins, corvids, and, more recently, in gibbons and macaques....
Soil Microbial Diversity and Network Organization Respond to Land Use and Agricultural Inputs WorldwideNARA Subscribed
Soil microbiomes are critical for ecosystem functioning, yet the global influences of climate and agricultural practices on their diversity and structure remain incompletely characterized. Here we analyzed 1921 soil samples from 33 countries worldwide across diverse biomes to assess how climate gradients and agricultural inputs, including pesticides and fertilizers, shape prokaryotic and fungal communities. We found that micro...
Drying Halves Decomposition Rates in River Networks by Decreasing Decomposer DiversityNARA Subscribed
River drying is intensifying worldwide due to climate change and increasing water abstraction, with major consequences for riverine biodiversity and ecosystem functioning. In river networks, drying not only alters local environmental conditions but also disrupts hydrological connectivity, reshaping the movement of organisms and resources at the river network scale. Leaf litter decomposition—a key ecosystem function in freshwat...
Among the most cultivated crops worldwide, potato ( Solanum tuberosum) faces significant threats from water scarcity, owing to its shallow root system and high irrigation requirement. Water deficit disturbs homeostasis and critical physiological mechanisms, including photosynthesis, carbohydrate translocation, and starch metabolism in tuberous plants. It reduces CO₂ assimilation, modulates the expression of key enzymes involve...
The androgenic gland (AG) is a male-specific endocrine organ in crustaceans, playing a crucial role in sexual differentiation. The function of the AG in decapods has been attributed to the expression of the insulin-like androgenic gland hormone ( IAG ) encoding gene which in Macrobrachium rosenbergii was shown to serve as a sexual switch (IAG-switch) for natural sexual differentiation as well as for sex manipulations. Macrobra...
Interpretable deep learning reveals spatiotemporal MRI features of brain aging that align with neurodegenerationNARA Subscribed
Cortical thinning and atrophy are hallmarks of brain aging that have been characterized using magnetic resonance imaging (MRI). Brain aging involves many neuroanatomic features whose effects on brain structure remain unexplored. To address this challenge, we trained interpretable deep neural networks (DNNs) to estimate brain age (BA) from T 1 -weighted ( T 1 w) MRI. By identifying MRI features unapparent to humans, DNNs can fi...