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Peripheral microRNA signature in genetic frontotemporal dementia—findings from the GENFI initiativeNARA Subscribed
Frontotemporal dementia (FTD) is a neurodegenerative disease characterized by significant clinical and genetic heterogeneity, with approximately 40% of cases linked to hereditary genetic mutations, including MAPT , GRN , and C9ORF72 . Recently, microRNAs (miRNAs) have emerged as key regulators of cellular processes related to neurodegeneration and as potential biomarkers for FTD. However, their relevance in presymptomatic stag...
Soil property controls on plasticiser, antioxidant and UV absorber additive degradation across a global soil gradientNARA Subscribed
Additives in agricultural plastics can leach into the surrounding soil during use or improper disposal. Their subsequent degradation rates directly regulate whether they persist and accumulate to levels with ecotoxicological effects or are rendered benign. However, which soil properties primarily regulate the degradation of additives remains unclear (e.g. soil carbon, pH, available nutrients, microbial biomass and community st...
Motivation Aquatic insects comprise 64% of freshwater animal diversity and are widely used as bioindicators to assess water quality impairment and freshwater ecosystem health, as well as to test ecological hypotheses. Despite their importance, a comprehensive, global database of aquatic insect occurrences for mapping freshwater biodiversity in macroecological studies and applied freshwater research is missing. We aim to fill t...
Microbial sensitivity to temperature and sulfate deposition modulates greenhouse gas emissions from peat soilsNARA Subscribed
Peatlands are among the largest natural sources of atmospheric methane (CH 4 ) worldwide. Microbial processes play a key role in regulating CH 4 emissions from peatland ecosystems, yet the complex interplay between soil substrates and microbial communities in controlling CH 4 emissions as a function of global change remains unclear. Herein, we performed an integrated analysis of multi‐omics data sets to provide a comprehensive...
Globalization has led to the introduction of thousands of alien species worldwide. With growing impacts by invasive species, understanding the invasion process remains critical for predicting adverse effects and informing efficient management. Theoretically, invasion dynamics have been assumed to follow an “invasion curve” (S‐shaped curve of available area invaded over time), but this dynamic has lacked empirical testing using...
Rapid changes in river plume dynamics caused by advected wind‐driven coastal upwelling as observed in Lake GenevaNARA Subscribed
Based on field investigations carried out in Lake Geneva during summer stratification in 2019, this study documents, for the first time, the rapid change of negatively buoyant river inflow dynamics caused by the passing of a coastal upwelling. Under calm conditions, the negatively buoyant Rhône River, entering at the eastern end of the lake, interacts with the lake density profile such that the river intrusion moves as an inte...
The conservation status of the world’s freshwater molluscsNARA Subscribed
The GenTree Leaf Collection: Inter‐ and intraspecific leaf variation in seven forest tree species in EuropeNARA Subscribed
Motivation Trait variation within species can reveal plastic and/or genetic responses to environmental gradients, and may indicate where local adaptation has occurred. Here, we present a dataset of rangewide variation in leaf traits from seven of the most ecologically and economically important tree species in Europe. Sample collection and trait assessment are embedded in the GenTree project (EU‐Horizon 2020), which aims at ch...
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