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Parasites play a critical yet understudied role in Arctic ecosystems, particularly within key subsistence species such as Arctic char ( Salvelinus alpinus ). As the Arctic undergoes rapid climate-driven change, establishing baseline parasite biodiversity is essential for monitoring ecological shifts and anticipating emerging health and conservation concerns. This study provides the most comprehensive assessment to date of Arct...
Purpose Virtual reality (VR) reduces experimental and clinical pain, but whether these effects extend to naturally occurring muscle pain (NOMP) during exercise remains unclear. This study examined whether immersive nature-based VR attenuates NOMP and improves motor performance during prescribed and self-regulated exercise. Methods Two within-participant crossover studies were conducted involving 12 (Study 1) and 24 (Study 2) h...
Bees forage and utilize centipedegrass pollenNARA Subscribed
Bees are crucial for pollination, producing 35% of the world’s fruits, nuts, and vegetables. However, the decline in bee populations due to habitat loss, monoculture farming, pesticide use, and urbanization threatens biodiversity and agricultural sustainability. Thus, it is critical to identify additional resources for pollinators. Centipedegrass ( Eremochloa ophiuroides ) is a common turfgrass in the southeastern United State...
Global patterns and regional insights into kelp forest protection, restoration, and stewardshipNARA Subscribed
Kelp forests are among the most extensive and productive coastal ecosystems, yet they remain underrepresented in global conservation policy despite widespread declines driven by interacting global- (i.e., ocean warming, marine heatwaves) to local-scale stressors. At the same time, kelp conservation and restoration efforts are expanding rapidly across regions, but measures of success and syntheses tend to primarily focus on eco...
Effectiveness of passive trapping and sweep netting for insect pollinator sampling in turf communitiesNARA Subscribed
Pollinator communities in urban and peri-urban turfgrass remain poorly characterized despite the ubiquity of lawns and growing interest in management practices that enhance floral resources within these otherwise resource-limited environments. To address this gap, we evaluated the effectiveness of active (sweep netting at multiple times of day) and passive (molasses traps and blue, white, and yellow pan traps) sampling methods...
Interpretable deep learning reveals spatiotemporal MRI features of brain aging that align with neurodegenerationNARA Subscribed
Cortical thinning and atrophy are hallmarks of brain aging that have been characterized using magnetic resonance imaging (MRI). Brain aging involves many neuroanatomic features whose effects on brain structure remain unexplored. To address this challenge, we trained interpretable deep neural networks (DNNs) to estimate brain age (BA) from T 1 -weighted ( T 1 w) MRI. By identifying MRI features unapparent to humans, DNNs can fi...
Genetic Legacy of the Last Ice Age Shapes Shallow Phylogeographic Structure in a Widespread Mediterranean SnakeNARA Subscribed
Aim Mediterranean peninsulas typically harbour high intraspecific genetic diversity associated with long‐term persistence in multiple glacial refugia. However, some widespread taxa show unexpectedly shallow phylogeographic structure. Here, we investigate which historical processes can generate a pattern of strong genetic depletion within a classic southern European refugial region. Location Iberian Peninsula and southern Franc...
The increasing magnitude and complexity of precipitation datasets necessitate robust and efficient data integrity assessment. This study systematically applies Benford's Law, a mathematical theorem describing leading digit frequencies, as a novel diagnostic tool for precipitation data in the environmental and hydroclimate sciences. We present a reproducible and robust methodology, demonstrating that global monthly precipitatio...
PQRI Workshop: Model-Informed Drug Development (MIDD) Approaches in Pediatric Formulation DevelopmentNARA Subscribed
In February of 2024, the Product Quality Research Institute held a virtual workshop entitled “Model-Informed Drug Development (MIDD) Approaches in Pediatric Formulation Development.” The workshop covered a range of topics related to pediatric formulation development and testing, including dissolution testing and applications to modeling drug absorption in developing pediatric patients. Workshop speakers reviewed the progress t...
Alzheimer’s disease (AD) disproportionately affects women and carriers of the apolipoprotein E ε4 allele (APOE4), yet little is known about how sex and APOE interact to influence white matter (WM) integrity during disease progression. We integrated diffusion MRI and matched blood transcriptomic data to investigate these interactions and their underlying biological mechanisms. WM microstructure was quantified using diffusion te...
Falls are a leading cause of injury in older adults, making risk prediction a clinical priority. While many machine learning (ML) models exist, they typically provide a static assessment, predicting risk for a single, fixed timeframe. This approach overlooks how the clinical drivers of risk evolve over time, failing to distinguish between acute factors that signal an imminent fall and chronic conditions that confer long-term v...
Marine megafauna species are affected by a wide range of anthropogenic threats. To evaluate the risk of such threats, species’ vulnerability to each threat must first be determined. We build on the existing threats classification scheme and ranking system of the International Union for Conservation of Nature (IUCN) Red List of Threatened Species by assessing the vulnerability of 256 marine megafauna species to 23 at‐sea threat...
The Toxicology Investigators Consortium 2024 Annual ReportNARA Subscribed
In recent decades, wildfire regimes have changed significantly, with increases in frequency, severity and area affected, leading to major habitat alterations that may impact species ecology. While fire's role in plant ecology is well studied, its effects on animal biotic interactions remain poorly understood. In northern Portugal, where wildfires are common, the native rock‐dwelling lizard Podarcis lusitanicus may thrive postf...
Anticipating the winds of change: A baseline assessment of Northeastern US continental shelf surficial substratesNARA Subscribed
The introduction of thousands of wind turbines along the North American Atlantic continental shelf over the next decade will constitute the largest regional change in marine substrates since the retreat of the Laurentide Ice Sheet over 14,000 years ago. Here, two large data sets, SMAST drop camera survey (242,949 samples, 2003 to 2019) and the US Geological Survey databases (27,784 samples, 1966 to 2011), are combined to deriv...
Salmonid fishes exhibit marked intra-specific variation in muscle pigmentation, primarily due to individual differences in the accumulation and assimilation of dietary carotenoids. Carotenoids are synthesized by primary producers and microorganisms, and present in the tissues of crustaceans that can serve as important prey for salmonids. Despite anadromous Arctic char ( Salvelinus alpinus ) being a key subsistence and economic...