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The italian national genomic strategy: current status, challenges, and future perspectives in clinical practice and public healthNARA Subscribed
This article presents the outcomes of a national initiative aimed at developing a technical document to support the future Italian National Genomic Strategy, carried out from 2021 to 2024 through the collaboration of 14 research institutions. The project was designed to align with major European genomic initiatives, particularly the “1 + Million Genomes” (1 + MG) Declaration and its supporting programs, including Beyond 1 Mill...
Key message The barley mutant xan-h.chli-1 shows phenotypic features, such as reduced leaf chlorophyll content and daily transpiration rate, typical of wild barley accessions and landraces adapted to arid climatic conditions. Abstract The pale green trait, i.e. reduced chlorophyll content, has been shown to increase the efficiency of photosynthesis and biomass accumulation when photosynthetic microorganisms and tobacco plants...
Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severityNARA Subscribed
The combined impact of common and rare exonic variants in COVID-19 host genetics is currently insufficiently understood. Here, common and rare variants from whole-exome sequencing data of about 4000 SARS-CoV-2-positive individuals were used to define an interpretable machine-learning model for predicting COVID-19 severity. First, variants were converted into separate sets of Boolean features, depending on the absence or the pr...
The Scent of Individual Foraging BeesNARA Subscribed
Aim To test whether within‐species and among‐species patterns of abundance and latitudinal range in marine bacteria resemble those found for macro‐organisms, and whether these patterns differ along latitudinal clines. Location Global pelagic marine environments. Methods Taxon‐specific sequence abundance and location were retrieved from the open‐access V6‐ rRNA pyrotag sequence data base VAMPS ( http://vamps.mbl.edu/ ), which h...
Fine mapping of 14q24.1 breast cancer susceptibility locusNARA Subscribed
Ecologists have long sought to understand the relationships among species diversity, community productivity and invasion by non‐native species. Here, four long‐term observational datasets were analyzed using repeated measures statistics to determine how plant species richness and community resource capture (i.e. productivity) influenced invasion. Multiple factors influenced the results, including the metric used to quantify in...
Neurocognitive Functioning in Posttraumatic Stress DisorderNARA Subscribed
On the U.S. west coast, the main toxin‐producing algal species are dinoflagellates in the genus Alexandrium that cause paralytic shellfish poisoning (PSP) and diatoms in the genus Pseudo‐nitzschia that produce domoic acid and cause domoic acid poisoning (DAP). Other harmful species, including the raphidophyte Heterosigma akashiwo and the diatoms Chaetoceros convolutus and Chaetoceros concavicornis, kill fish at aquaculture sit...
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