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NARA Subscribed1
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Springer Nature1
Journal
Translational Stroke Research1
Publication Year
20251
David Howat results 1 · Newest (Page 1/1, per page 25)
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A Randomised Controlled Trial of SFX-01 After Subarachnoid Haemorrhage — The SAS StudyNARA Subscribed
Translational Stroke Research · 2025 · Vol. 16 · Issue 4 · Springer
Ardalan Zolnourian; Patrick Garland; Patrick Holton; Mukul Arora; Jonathan Rhodes; Christopher Uff; Tony Birch; David Howat; Stephen Franklin; Ian Galea; Diederik Bulters
SFX-01 is a novel drug for clinical delivery of sulforaphane (SFN). SFN is a potent nuclear factor erythroid 2-related factor 2 activator that reduces inflammation and oxidation, improving outcomes after subarachnoid haemorrhage (SAH) in animal models. This was a multi-centre, double-blind, placebo-controlled, parallel-group randomised clinical trial to evaluate the safety, pharmacokinetics and efficacy of 28 days of SFX-01 30...
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