Tuberculosis (TB) treatment is highly effective, but response to therapy varies by geography and population subgroups. We assessed differences in TB treatment response in a representative and heterogeneous Brazilian population. We estimated genetic ancestry according to major genetic ancestry groups (African, European, and Amerindian) in the Regional Prospective Observational Research in Tuberculosis (RePORT)-Brazil cohort usi...

Keymessage Standardized microhaplotype databases for eight diverse crops enable multiallelic analyses, comparative genetics, and breeding decisions. Abstract Microhaplotypes are short genomic segments that contain multiple tightly linked variants, providing multi-allelic data that can enhance genetic resolution compared to traditional biallelic single nucleotide polymorphism (SNP) markers. Here, we present the creation and uti...

Species interactions among multiple invasive species can present hidden challenges for management and eradication efforts. Bighead and Silver carp ( Hypophthalmichthys nobilis and H. molitrix , respectively) are closely related species that have co-invaded the Mississippi River and many of its tributaries, including the Illinois River. We used a combination of causal inference and dynamic models to test for interspecific inter...

Muscle fascicle length is a key determinant of sprint performance, with lengthening adaptations observed following eccentric strength training or combined sprint and resistance interventions. However, whether sprint-focused training can induce meaningful architectural adaptations, independent of concurrent sport-related training, remains unclear. Fourteen participants (10 female, 4 male; age 21.6 ± 3.3 years; body mass 68.0 ±...

In July 2022, a harmful algal bloom of Heterosigma akashiwo originated in a man-made lagoon and expanded to more than 4,500 km² of open-water habitat in the San Francisco Estuary, triggering a widespread mass mortality event involving bony fishes, sharks, rays, crustaceans, mollusks, polychaetes, and jellyfish. Notably, the event affected the southernmost spawning populations of White Sturgeon ( Acipenser transmontanus ) and f...