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Springer Nature1
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GeroScience1
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20261
David Lukacsovich results 1 · Newest (Page 1/1, per page 25)
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The aging epigenome: integrative analyses reveal intersection with Alzheimer’s diseaseNARA Subscribed
GeroScience · 2026 · Vol. 48 · Issue 3 · Springer
Wei Zhang; David Lukacsovich; Juan I. Young; Lissette Gomez; Michael A. Schmidt; Brian W. Kunkle; Xi Chen; Eden R. Martin; Lily Wang
Aging is the strongest risk factor for Alzheimer’s disease (AD), yet the role of age-associated DNA methylation (DNAm) changes in blood and their relevance to AD remains poorly understood. We performed a meta-analysis of blood DNAm samples from 475 dementia-free subjects aged over 65 years across two independent cohorts, the Framingham Heart Study (FHS) at Exam 9 and the Alzheimer’s Disease Neuroimaging Initiative (ADNI). We a...
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