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Sequence analyses to accelerate the development of rapid resistance assays targeting the Neisseria gonorrhoeae gyrA geneNARA Subscribed
Purpose Mutations in the Neisseria gonorrhoeae (NG) gyrA codons 91 and 95 are known to confer resistance to ciprofloxacin, but questions remain over whether all the various permutations of these codons are needed for optimal molecular detection of NG ciprofloxacin susceptibility. Here, we used publicly available sequence data to answer this question to help inform the design of next-generation NG gyrA assays. Methods NG gyrA a...
Diversity of Mycoplasma genitalium strains in Australia: relationship with sexual networks and antimicrobial resistanceNARA Subscribed
Purpose Molecular typing can identify relationships between M. genitalium strains and antimicrobial resistance and demographic data. We examined the association of mgpB sequence types (STs) with sex/sexual orientation, antimicrobial resistance and geographical location for M. genitalium in Australia. Methods Sequence data derived from previous studies in Victoria and Queensland were obtained from 170 M. genitalium samples for...
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