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Parasites play a critical yet understudied role in Arctic ecosystems, particularly within key subsistence species such as Arctic char ( Salvelinus alpinus ). As the Arctic undergoes rapid climate-driven change, establishing baseline parasite biodiversity is essential for monitoring ecological shifts and anticipating emerging health and conservation concerns. This study provides the most comprehensive assessment to date of Arct...
Standardized microhaplotype databases and frameworks for assessing and mining crop genetic diversityNARA Subscribed
Keymessage Standardized microhaplotype databases for eight diverse crops enable multiallelic analyses, comparative genetics, and breeding decisions. Abstract Microhaplotypes are short genomic segments that contain multiple tightly linked variants, providing multi-allelic data that can enhance genetic resolution compared to traditional biallelic single nucleotide polymorphism (SNP) markers. Here, we present the creation and uti...
A primary care pharmacogenetic precision medicine pilot based on specific Māori tribal ethical frameworks and principlesNARA Subscribed
Indigenous tribal communities are frequently underserved by genomic medicine because they are under-represented in research, often live in remote locations and have ethical and cultural perspectives that vary from westernised standpoints. The Rakeiora platform, a permissioning and analytical environment that incorporates Māori perspectives and ethical frameworks on how precision medicine research is best conducted was used to...
Stratigraphic evidence of organic carbon depletion in an intensely trawled muddy seabedNARA Subscribed
Understanding the long-term effects of bottom trawling on sedimentary organic carbon (OC) is crucial for assessing its role in carbon cycling and climate regulation. Most studies analyse effects on surface sediments (≤10 cm), leaving impacts on deeper sediments poorly resolved. This study investigates how bottom trawling influences sediment OC density (SCD) and OC content within 0–50 cm of the Western Irish Sea Mud Belt, repre...
Interpretable deep learning reveals spatiotemporal MRI features of brain aging that align with neurodegenerationNARA Subscribed
Cortical thinning and atrophy are hallmarks of brain aging that have been characterized using magnetic resonance imaging (MRI). Brain aging involves many neuroanatomic features whose effects on brain structure remain unexplored. To address this challenge, we trained interpretable deep neural networks (DNNs) to estimate brain age (BA) from T 1 -weighted ( T 1 w) MRI. By identifying MRI features unapparent to humans, DNNs can fi...
Between quiescence and crisis: Hawaiian Volcano Observatory communication and response strategies on the Island of HawaiʻiNARA Subscribed
Over the past two centuries, eruptions of Mauna Loa volcano have damaged infrastructure and destroyed several communities on the Island of Hawaiʻi. Future eruptions will impact existing population centers and critical infrastructure, which continue to grow each year. The U.S. Geological Survey Hawaiian Volcano Observatory has developed and practiced methods to promote eruption preparedness in communities on the Island of Hawai...
Diagnosing scaling bottlenecks in 10 community conservation initiatives in southern and eastern AfricaNARA Subscribed
Scaling area‐based conservation, including initiatives led or comanaged by Indigenous Peoples and local communities, is a flagship goal of the Kunming‐Montreal Global Biodiversity Framework. Conservationists often aspire to scale initiatives, but this is rarely achieved in practice. Identifying and addressing factors that limit initiative adoption (i.e., bottlenecks) could improve scaling strategies. We used insightsfrom 84 ex...
Introduction Picocyanobacteria from the genera Prochlorococcus and Synechococcus thrive across the globe in aquatic environments, have relatively small genomes, and have growth dynamics regulated by both viral interactions and abiotic conditions, making them excellent model organisms for exploring host-pathogencoevolution. Methods We developed and refined methods to sample and sequence cyanobacteria, cyanophages, and measured...
Alzheimer’s disease (AD) disproportionately affects women and carriers of the apolipoprotein E ε4 allele (APOE4), yet little is known about how sex and APOE interact to influence white matter (WM) integrity during disease progression. We integrated diffusion MRI and matched blood transcriptomic data to investigate these interactions and their underlying biological mechanisms. WM microstructure was quantified using diffusion te...