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Groundwater is a critical freshwater resource, but its quality can be compromised by anthropogenic contamination. Metals may exert selective pressure on microbial communities, promoting metal-tolerant bacteria carrying metal tolerance genes (MTGs), which are often associated with antimicrobial resistance genes (ARGs) and virulence determinants. Therefore, this study aimed to investigate Gram-negative opportunistic bacteria fro...
Tissue-specific oxidative responses and recovery following acute thermal stress in juvenile Amazonian fish Colossoma macropomumNARA Subscribed
Colossoma macropomum (tambaqui) is an economically important Amazonian fish increasingly exposed to heatwaves in tropical aquaculture systems. However, multi-tissue responses to acute thermal stress and recovery remain poorly understood. Juveniles were exposed to 34 °C for 24 h, with samples collected at baseline and at 1, 24, and 48 h post-recovery (28 °C). Antioxidant responses and oxidative damage markers were evaluated to...
Selection and Characterization of Novel Glucuronoxylomannan-Mimetic Peptides for Potential Diagnosis of CryptococcosisNARA Subscribed
Cryptococcus neoformans is an encapsulated fungal pathogen characterized by a thick polysaccharide capsule, primarily composed of glucuronoxylomannan (GXM), which represents its major virulence factor and a key target for immunodiagnosis. Mimetic peptides that reproduce GXM epitopes may provide standardized, stable alternatives to native polysaccharide antigens for diagnostic and therapeutic applications. This study aimed to i...
Bio‐oceanographic modeling and population genomics were combined to assess connectivity of the blue crab Callinectes sapidus in the Southwestern Atlantic Ocean, with particular attention to the scale of its fishery management, and the potential role of Marine Protected Areas (MPAs) in Uruguay as larval source zones. A bio‐physical model, coupled with hydrodynamic outputs of a model experiment, incorporated larval vertical migr...
Dynamic stability in phytoplankton through size-based compensation under ENSO extremesNARA Subscribed
Climatic extremes associated with the El Niño–Southern Oscillation (ENSO) reorganize aquatic communities, but whether such reassembly translates into functional restructuring remains unclear. A 25-year phytoplankton time series (2001–2025) from Lake Mangueira, a large subtropical shallow lake in southern Brazil, was used to test whether El Niño and La Niña drive shifts in size-based functional structure or primarily taxonomic...
Among the most cultivated crops worldwide, potato ( Solanum tuberosum) faces significant threats from water scarcity, owing to its shallow root system and high irrigation requirement. Water deficit disturbs homeostasis and critical physiological mechanisms, including photosynthesis, carbohydrate translocation, and starch metabolism in tuberous plants. It reduces CO₂ assimilation, modulates the expression of key enzymes involve...
Lepidocybium flavobrunneum [Smith, 1843], commonly known as escolar, is a large pelagic species, important for global and local fisheries, particularly in the southwestern South Atlantic Ocean (SWAO), where it constitutes a significant portion of the catch. However, despite its important socioeconomic role, it remains less studied compared to other large pelagic species. Enhancing research efforts is therefore key to better un...
Integration of Multi-Omics Data To Understand the Multifaceted Role of RAMP1 across Different Cancer TypesNARA Subscribed
Receptor Activity-Modifying Protein 1 (RAMP1) is a Calcitonin Receptor-Like Receptor (CALCRL)-associated protein with significant relevance in oncogenesis and tumor progression. It acts as a context-dependent allosteric modulator of GPCRs. This integrative review synthesizes evidence from multiple omics layers—transcriptomics, proteomics, epigenomics, and pan-cancer datasets—to clarify the role of RAMP1, its signaling pathways...
Circular and Sustainable Business Model Innovation: Formulating an Integrated Concept Through A Systematic Literature ReviewNARA Subscribed
Despite the significant growth in research on the triad of Circular Economy (CE), Innovation, and Sustainable Business Models (SBMs), theoretical fragmentation persists due to the lack of holistic conceptual integration, resulting in a heterogeneous framework that is difficult to apply in practice. Given this scenario, this study aimed to identify, categorize, and systematize the state of the art of Circular Economy, Innovatio...
Emerging co-occurrence of mcr-10 and broad-spectrum β-lactamase genes in Enterobacterales from surface waters in BrazilNARA Subscribed
Aquatic ecosystems play a key role in the spread of antimicrobial resistance genes (ARGs), especially mcr -type and β-lactamase genes. The occurrence of β-lactamases and the mcr-10 genes has emerged among Enterobacterales species across the world; however, this phenomenon had never been reported in Brazil until now. We performed a surveillance study focusing on the spread of the mcr -type genes in WHO critical bacterial priori...