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Soil organic carbon (SOC) sequestration is vital for food security and climate mitigation. However, its long‐term response to fertilisation remains unclear. Using the 180‐year Broadbalk Experiment (the world's longest‐running fertilisation trial; Rothamsted, UK), combined with 14 C labelling and metagenomics, we identified fundamentally distinct mechanisms of SOC accumulation: a microbially mediated dual pathway under organic...
Peripheral microRNA signature in genetic frontotemporal dementia—findings from the GENFI initiativeNARA Subscribed
Frontotemporal dementia (FTD) is a neurodegenerative disease characterized by significant clinical and genetic heterogeneity, with approximately 40% of cases linked to hereditary genetic mutations, including MAPT , GRN , and C9ORF72 . Recently, microRNAs (miRNAs) have emerged as key regulators of cellular processes related to neurodegeneration and as potential biomarkers for FTD. However, their relevance in presymptomatic stag...
Increased Soil Carbon and Nitrogen Stocks Associate With Stronger Calcium–Microbial and Multi‐Trophic Interactions Under WarmingNARA Subscribed
Converting cropland to planted forests improves soil organic carbon (SOC) and total nitrogen (TN) storage while contributing to climate change mitigation, primarily through the regulation of belowground organisms and mineral protection such as calcium (Ca). However, the mechanistic pathways linking exchangeable Ca 2+ , soil micro‐food web interactions, and nutrient accumulation under warming remain unclear. Here, we investigat...
The Toxicology Investigators Consortium 2024 Annual ReportNARA Subscribed