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Investigation of blood–brain barrier penetration and pharmacokinetics of a new formulation of cyanide antidote dimethyl trisulfideNARA Subscribed
Objective During cyanide poisoning, the rescue of vital organs like the brain is urgent. However, due to the presence of the blood–brain barrier (BBB), the currently available cyanide antidotes cannot reach the brain. Dimethyl trisulfide (DMTS) is a potent cyanide antidote and has excellent BBB permeability. Nonetheless, its formulation and application are challenging due to its highly lipophilic profile. In this work, a novel...
The World Meteorological Organization Aircraft Meteorological Data Relay (AMDAR) programme refers to meteorological data gathered by commercial aircraft and made available to weather services. It has become a major source of upper-air observations whose assimilation into global models has greatly improved their performance. Near busy airports, AMDAR data generate semi-continuous vertical profiles of temperature and winds, whic...
Flow Separation in the Lee of a Crater RimNARA Subscribed
Increased Arctic sea ice drift alters adult female polar bear movements and energeticsNARA Subscribed
Recent reductions in thickness and extent have increased drift rates of Arctic sea ice. Increased ice drift could significantly affect the movements and the energy balance of polar bears ( Ursus maritimus ) which forage, nearly exclusively, on this substrate. We used radio‐tracking and ice drift data to quantify the influence of increased drift on bear movements, and we modeled the consequences for energy demands of adult fema...
Tea consumption and risk of ovarian cancerNARA Subscribed