Mitochondrial transcription factor A (TFAM) is indispensable for mitochondrial DNA (mtDNA) maintenance and transcription, governing cellular bioenergetics. Despite its known physiological importance, TFAM plays a complex and often paradoxical role in cancer biology. This study integrates pan-cancer bioinformatics analyses with experimental evidence to comprehensively elucidate TFAM’s multifaceted impact on tumorigenesis. We sy...

Near real-time monitoring of faecal indicator bacteria (FIB) in waters is currently not feasible, and current monitoring methods require field sampling and laboratory testing that inhibits decision-making within a relevant timeframe. While recent studies identified the potential of using specific fluorescence regions for FIB monitoring, sufficient accuracy often requires site-specific calibration due to minor variations in flu...