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Dirk Westermann results 5 · Newest (Page 1/1, per page 25)
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ADP as a novel stimulus for NLRP3-inflammasome activation in mice fails to translate to humansNARA Subscribed
Purinergic Signalling · 2024 · Vol. 20 · Issue 3 · Springer
Julius Wissemann; Adrian Heidenreich; Helene Zimmermann; Juliane Engelmann; Jasper Jansen; Dymphie Suchanek; Dirk Westermann; Dennis Wolf; Peter Stachon; Julian Merz
The NLRP3-inflammasome is a cytosolic multiprotein complex that triggers an inflammatory response to certain danger signals. Recently adenosine diphosphate (ADP) was found to activate the NLRP3-inflammasome in murine macrophages via the P2Y 1 receptor. Blockade of this signaling pathway reduced disease severity in a murine colitis-model. However, the role of the ADP/P2Y 1 -axis has not yet been studied in humans. This present...
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Molecular mechanisms underlying NLRP3 inflammasome activation and IL-1β production in air pollution fine particulate matter (PM2.5)-primed macrophagesNARA Subscribed
Environmental Pollution · 2024 · Vol. 341 · Elsevier
Lourdes Caceres; Tijani Abogunloko; Sara Malchow; Fabienne Ehret; Julian Merz; Xiaowei Li; Lucia Sol Mitre; Natalia Magnani; Deborah Tasat; Timothy Mwinyella; Lisa Spiga; Dymphie Suchanek; Larissa Fischer; Oliver Gorka; Mark Colin Gissler; Ingo Hilgendorf; Peter Stachon; Eva Rog-Zielinska; Olaf Groß; Dirk Westermann; Pablo Evelson; Dennis Wolf; Timoteo Marchini
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Transgenic overexpression of adenine nucleotide translocase 1 protects ischemic hearts against oxidative stressNARA Subscribed
Journal of Molecular Medicine · 2016 · Vol. 94 · Issue 6 · Springer
Inga Klumpe; Konstantinos Savvatis; Dirk Westermann; Carsten Tschöpe; Ursula Rauch; Ulf Landmesser; Heinz-Peter Schultheiss; Andrea Dörner
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Cardiac-targeted RNA interference mediated by an AAV9 vector improves cardiac function in coxsackievirus B3 cardiomyopathyNARA Subscribed
Journal of Molecular Medicine · 2008 · Vol. 86 · Issue 9 · Springer
Henry Fechner; Isaac Sipo; Dirk Westermann; Sandra Pinkert; Xiaomin Wang; Lennart Suckau; Jens Kurreck; Heinz Zeichhardt; Oliver Müller; Roland Vetter; Volker Erdmann; Carsten Tschope; Wolfgang Poller
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Renin inhibitors, clinical experienceNARA Subscribed
Journal of Molecular Medicine · 2008 · Vol. 86 · Issue 6 · Springer
Dirk Westermann; Roland Schmieder; Heinz-Peter Schultheiss; Carsten Tschöpe
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