Oral lichen planus (OLP) is a chronic inflammatory disorder with limited topical treatment options and long-term corticosteroid dependency. This study investigates a novel atorvastatin-loaded hyalurosomal gel (ATV-Hyalugel) as a topical adjuvant to reduce systemic corticosteroid use in severe OLP. The objective of the study is to develop, optimize, characterize ATV-Hyalugel and evaluate its clinical efficacy in a randomized co...

The current global context stimulating agroecology and green agriculture need to explore for the novel sustainable and eco-conscious methods for safeguarding plants. The aim of this study is to exploit the rich contents of date palm seeds (DPS) as an appropriate organic elicitor to boost growth and plant secondary metabolism in Eruca vesicaria . The seeds of DPS were utilized in the extraction process using distilled water to...

Identifying novel natural sources from the marine environment with unique immunomodulatory and antioxidant efficacies is of interest in intensive fish farming. In this sense, marine sponge extract derived from Smenospongia (SS-extract) was tested for its potential anti-inflammatory, antioxidant and antimicrobial activities during the concurrent infection with Trichodina sp. and Flavobacterium columnare in Nile tilapia. A total...

Quinoline motifs are essential in several pharmacological active heterocyclic compounds due to their various applications in medicinal and industrial chemistry. Furthermore, there are greater societal expectations in the current scenario that synthetic and medicinal chemists should produce greener and more sustainable chemical processes. Therefore, this mini-review article highlights the traditional and green synthetic approac...