Conservation of large carnivore populations requires effective management strategies that promote landscape-scale protection and genetic connectivity. Pivotal to the success of these strategies is sufficient evidence, including quantifying the processes that govern species distribution. We used telemetry data from 63 lions from the Kavango-Zambezi Transfrontier Conservation Area (KAZA TFCA) in southern Africa to analyze inter-...

Obesity is associated with alterations in brain structure and function, particularly in areas related to reward processing. Although brain structural investigations have demonstrated a continuous association between higher body weight and reduced gray matter in well-powered samples, functional neuroimaging studies have typically only contrasted individuals from the normal weight and obese body mass index (BMI) ranges with mode...

Purpose Two to seven percent of the German adult population has a renal impairment (RI) with an estimated glomerular filtration rate (eGFR) < 60 ml/min/1.73m 2 . This often remains unrecognized and adjustment of drug therapy is lacking. To determine renal function in clinical routine, the CKD-EPI equation is used to calculate an indexed eGFR (ml/min/1.73m 2 ). For drug dosing, it has to be individualized to a non-indexed eGFR...