Studying the mechanism of hematopoietic stem cells’ generation from induced pluripotent stem cells in vitro can be useful for understanding embryonic hematopoiesis, as well as for the application of related cell therapy. This study aimed to delineate the process of the differentiation of induced pluripotent stem cells into hematopoietic stem cells’ models and provide a theoretical basis and clinical value for the production of...

Sichuan Province spawned abundant of indigenous buffalo varieties, which probably harbor valuable gene resources beneficial to the genetic improvement of buffalo. However, limited genetic information was publicly available. To better understand their selection signatures between different populations, we performed a restriction site-associated DNA sequencing (RADseq) to explore genome-wide SNPs among two indigenous breeds of S...