E. Cheng results 370
· Newest (Page 1/15, per page 25)
Author: E. Cheng ×Clear All Filters
Search Results
Neutrophil-related gene expression profile is associated with future paediatric bronchiectasis exacerbationsNARA Subscribed
Acute respiratory exacerbations in bronchiectasis are important as they impair quality of life and are associated with accelerated lung function decline. Yet, no validated methods exist to identify children at increased risk of exacerbations. We therefore determined if peripheral blood gene expression (GE) signatures can identify those at risk of an impending exacerbation. Thirty-one children with bronchiectasis had RNA extrac...
Purpose Tacrolimus (TAC) is known for its high pharmacokinetic variability which cannot be fully explained by pharmacogenomic (PGx) and clinical variables. We identified gut microbiome associated with TAC pharmacokinetic variability in allogeneic hematopoietic cell transplant (HCT) recipients. Methods In this observational study, metagenomic shotgun sequencing was used to analyze stool microbiome collected within ± 10 days fro...
Microbial Functional Gene Abundance‐Integrated Modeling of Global Methane Sinks in Upland Soils Under Future Climate ChangeNARA Subscribed
Methanotrophs are key microbial regulators of soil methane (CH 4 ) sinks, but the global impact of their functional gene abundance on CH 4 oxidation remains unquantified. This gap limits the integration of key functional genes abundance parameters (e.g., pmoA ) into soil CH 4 sink model. We integrated meta‐analysis, machine learning, and process‐based modeling to assess the relationship between pmoA gene abundance and soil CH...
Precision measurement of the Ds*+-Ds+ meson mass differenceNARA Subscribed
Ocean dissolved oxygen (O2) is an essential climate variable crucial for sustaining the marine life; thus, changes of O2 at various spatiotemporal scales should be quantified and understood. Here, we study the climatology and annual cycle of O2 at regional to global scales using eight available gridded observational products. These datasets are generated by different groups using different primary data selection, quality contr...
Pacific bluefin tuna ( Thunnus orientalis , PBF) are highly migratory, with a single Pacific‐wide stock facing complex management challenges due to extensive transoceanic movements and a recent population recovery. This study addresses persistent knowledge gaps regarding the quantitative contributions of different natal origins to key feeding grounds and the proportions of trans‐Pacific migrants in spawning grounds. We used st...
Aim The temperature‐size rule is often described as a reduction in ectothermic asymptotic or maximum body size with warming. Although this coincides with the expectation that faster growth under warming would lead to larger sizes early in life but smaller sizes later in life, there remain few tests of changes in size across ontogeny. Here, we use > 99,000 observations of weight‐at‐age of commercially important fishes over 25 y...